- All our products are fresh and have long expiry dates for shipping. It can also cause less serious side effects in dogs, such as irritation at the spot of application, diarrhea, vomiting and seizures. Waiver Requests for Acute Mammalian Toxicity Data Inert ingredient info on pages 2, 3, 4 not included. This chemical is extremely effective when used for several different types of insects and pests, which include: When methoprene is used in insecticides specifically for your cat, it may be referred to as Zodiac, Biospot and Frontline. If he itching does not subside within a few hours, you may need to visit a veterinarian, as this too may be an indication of an allergic reaction. © All rights reserved. EPA is investigating these incidents and evaluating domestic animal safety data for Methoprene to Stay tuned to our updates and special offers. ... For cats with, or at risk from mixed infestations by cestodes, nematodes and ectoparasites. hours of application, an outstanding level of efficacy and the reason many vets recommend this Methocarbamol (50-150mg/kg IV bolus, titrate up as needed, but do not exceed 330mg/kg/d) works best to control the tremors. Methoprene is available in over 500 pesticide products, m… 4 Page(s). Studies into the use April 24, 2006. animals. S-Methoprene | C19H34O3 | CID 1711973 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Using S-Methoprene for Loss of Hair For some cats, loss of hair will appear where the medication is applied. 2. Incidents of toxicity to cats from the use of products containing Methoprene have been reported to the Agency. particular product. May cause eye, skin, or respiratory system irritation. MRID 46763209. In Frontline Plus, S-Methoprene is presented in single application format or as a spray, both of which of S-Methoprene showed that it works most efficiently when combined with another active ingredient which Flea bombs are toxic to cats, people, and goldfish, but rarely bring flea infestations completely under control. Knowing what these side effects are and understanding their effect may help you to determine if it is the right product for eradicating your cat’s flea or pest problem. breeding adults. By shopping online with Pet Shed you can be sure that your details are not compromised - we encrypt every transaction to the highest global standards.This site is secured by 256 bit SSL encryption. integrated HAZARDS IDENTIFICATIONS OSHA HCS CLASSIFICATION (29 CFR 1910.1200) Acute Toxicity: (S)-(+)-Methoprene SAFETY DATA SHEET Supersedes Revision: 02/04/2015 according to Regulation (EC) No. Toxicity concerns from overexposure or ingestion of current topical spot-on products come primarily from the adulticidal component of the product rather than methoprene. cyphenothrin, phenothrin, permethrin, etc.). advantage The chemical also kills flea eggs by stopping them from hatching. market. ... For cats with, or at risk from mixed infestations by cestodes, nematodes and ectoparasites. are applied directly to the animal's skin. It not only made the cat drool, but was ineffective for fleas. S-Methoprene is a chemical which is used for insect control, in particular fleas. you. s-Methoprene TG According to Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice, February 2016 SECTION 1: Identification: Product identifier and chemical identity Product identifier Product name s-Methoprene TG Chemical name isopropyl (E,E)-(7S)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate CAS number 65733-16-6 The three-generation reproductive toxicity study produced an increase in liver weights Understanding the effects that methoprene can have on your cat can help you determine if this will be an effective flea treatment. they are now drying and scabbing, so on the road to healing. S-Methoprene | C19H34O3 | CID 1711973 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. We've sourced the best products available, from the leading producers and manufacturers, and placed them all in the one spot for your selection. (S)-Methoprene is an insect growth regulator, or more precisely, a juvenile hormone mimic. Redness If your cat is constantly scratching the area of application, you are likely to notice redness appear. Frontline Plus for dogs or cats and Startgard Plus for puppies or kittens). This look can actually last for up to 24 hours while the product absorbs into the cats skin. S-Methoprene (3.6%). Selling discount flea control, heartworm treatments & pet meds for dogs and cats since 2002. MRID No. Rather than killing insects, it controls them by interfering with normal hormone levels within the insect at critical development periods preventing growth and/or maturation. Dosing Information of Fipronil and Methoprene for Dogs and Cats Medication should never be administered without first consulting your veterinarian. In the fine print it does say that cholinergic symptoms can include vomiting. Glow jewelry and sticks. Frontline Plus Deliveries are currently taking longer than usual. EPA is investigating these incidents and evaluating domestic animal safety data for Methoprene to The most common clinical signs of permethrin toxicity in cats are muscle tremors and seizures. Document (PDF) (175 KB PDF). my niece's 5 pound cat, 6 year old, was given hartz flea and tick control containing 3.6% (S) methoprene, and 40% etofenprox. 1907/2006 as amended by (EC) No. Fipronil also has high sub-acute toxicity with a 5-day dietary LC 50 of 49 mg/kg in bobwhite quail. 1; Fipronil is practically non-toxic to mallard ducks with no documented acute, sub-acute, or chronic effects. In a study with a formulation containing 20% S-methoprene, skin sensitization was seen; however, it was unclear whether the effect was due to S-methoprene or to another compound in the formulation. September 26, 2006. When it comes to taking benefits on household pets, it is best to use a well-known and proven product such as Frontline Plus. Poison Control Center Phone: 1-800-222-1222 . (S)-methoprene alone is well tolerated by dogs and cats, with a low toxicity and high safety margin. Frontline Plus for Cats . 46725801. Permethrin is toxic to cats; however, it has little effect on dogs. The product is for external use only. doses were available for (S)-methoprene, JMPR made the conservative assumption that, in the absence of any information to the contrary, all the toxicity of the racemate was due to the S enantiomer. 14 Page(s). Hypersalivation, depression, vomiting, anorexia and even death may also be seen. This could be permanent or temporary. DER. Identification of the Substance/Mixture and of the Company/Undertaking Product Name: (S)-(+)-Methoprene Company Name: Cayman Chemical Company Glow jewelry and sticks are plastic bracelets, necklaces, and wands that … It covers oral, topical and injectable medications suitable for cats and dogs. The insecticide In a parallel design study, one group of eight cats was treated with the combination product, fipronil 8.3% (w/v), (S)-methoprene 10% (w/v), eprinomectin 0.4% (w/v) and praziquantel 8.3% (w/v) (Broadline ®, Merial), once topically at 0.12 mL/kg bodyweight delivering a dose of 0.5 mg eprinomectin per kg bodyweight, and one group of six cats … The product is for external use only. Fipronil is highly toxic to bobwhite quail and pheasants, with an acute oral LD 50 of 11.3 mg/kg and 31.0 mg/kg, respectively. The collar secretes this insecticide that sinks into your cat’s skin that may kill or repel fleas. Frontline contains the active ingredients fipronil and s-methoprene. animals. 866-430-2823 She is a smallish slim cat, the others are quite big cats. Combining insecticides which work on all stages of the flea life cycle is called >2000 mg/kg. Cats. fact one of the active ingredients in the popular Check out this simple infographic that lays out the basic schedule for dog vaccines. Caution is needed when using the product on pregnant, nursing, aged, debilitated, or sensitive felines. Some of the most effective biological enemies of mosquitoes that you can buy, interfere with the growth of […] Consistent Itching - After applying methoprene to your cat, you may notice they have a consistent itch. for dogs and Incidents of toxicity to cats from the use of products containing Methoprene have been reported to the Agency. Vital information given for each drug includes: indications, contraindications, mechanism of action, dosage, formulations, side-effects, drug interactions and monitoring. Methoprene is not toxic to the pupal or adult stages. Toxic effects can be potentiated after simultaneous exposure to organophosphates or other synthetic pyrethroids. No toxic effects were observed in laboratory animals exposed to methoprene over time in their feed or on their skin. An insect growth regulator, (S)-methoprene [90 g/L (9%) for dogs or 120 g/L (12%) for cats], has also been included with several of the products containing fipronil (e.g. A Temporary Area of Irritation - There are some cats that will experience slight irritation where the medication is applied. Unless you are a vet or have studied chemistry, it is unlikely that the name S-Methoprene means much to Angela Gonzales. Flea collar vs drops for cats. On this basis, JMPR established an ADI for (S)-methoprene of 0–0.05 mg/kg of Our dedicated team is passionate about pets and will endeavour to keep you informed of the latest and relevant news and information about your pets.Our stock moves fast! Some of the side effects that may appear on your cat with the use of methoprene include: Appearance of the Fur - The fur of your cat may look oily or wet directly after the treatment is applied. S-Methoprene is a chemical which is used for insect control, in particular fleas. To be effective, it is essential that this growth inhibitor be administered at the proper stage of the target pest's life cycle. an adult. If the irritation does not fade relatively quickly, you should take your cat to a veterinarian, as it could indicate the presence of an allergic reaction. The day i removed it she stopped vomiting. Document (PDF) (108 KB PDF). Generic Frontline Plus (Fipronil & S-Methoprene) Selling discount flea control, heartworm treatments & pet meds for dogs and cats since 2002 Call Us! 2.1.2. Animals treated topically can ingest etofenprox through licking or grooming (particularly cats). It works by not allowing the target insect from reaching the point of maturity, which will halt the potential that it can reproduce. May be harmful by inhalation, ingestion, or skin absorption. Methoprene stops mosquitoes from growing, prevents larvae from becoming adults Safe for people, mammals, birds, not good for frogs, fish, crustaceans Altosid, containing methoprene, is a good choice to buy for treating mosquito larvae in watering troughs. and released gradually over an extended period. The active ingredients are absorbed into the skin and hair, In general, cats have a low tolerance for NSAIDs. S-methoprene mimics the fleas’ hormones and keeps them from reaching adulthood and reproducing. There is limited published information detailing adverse effects of methoprene in dogs or cats; however, given the mechanism of action, clinical effects are expected to be mild. She is a smallish slim cat, the others are quite big cats. Many cats die after being given flea treatments intended for dogs, or by contact with dogs having recently been treated with permethrin. for cats. Never use spot-ons or other products on cats that are approved only for dogs: synthetic pyrethroids can be toxic to cats. However, if you are a dog or cat owner, you might be interested to learn that S-Methoprene is in They keep flea eggs from developing into adult fleas that can suck your cat’s blood. Both American and European trade names are provided alongside generic names for ease of reference. LD50 acute, rats, dermal, >2000 mg/kg LD50 acute, dogs, dermal, >5000 mg/kg Etofenprox is less irritant than most pyrethroid esters (e.g. The two-generation reproductive toxicity study resulted in reduced weight gains and increases in adrenal gland weights. It comes in two different forms called s-methoprene and r-methoprene, and s-methoprene is the one that behaves like an important hormone in insects. Once you've placed your order, our team will handpick your order and arrange delivery of your goods right to your door. This look can actually last for up to 24 hours while the product absorbs into the cats skin. Pesticide-grade permethrin is toxic to cats. These collars release a toxic gas to kill or prevent fleas from going on your cat. Poisoning by (S)-methoprene alone is rare due to its low toxicity. A flea collar is used to repel fleas and kill them altogether. Efficacy Review. Caution is needed when using the product on pregnant, nursing, aged, debilitated, or sensitive felines. they are now drying and scabbing, so on the road to healing. In cats it may induce hyperexcitability, tremors, seizures, and … It can be used against fleas, flies, moths, beetles, and other insects. Though the EPA has received reports of IGR toxicity in cats, those reports are still under investigation. What this means is that Hypersalivation, depression, vomiting, anorexia and even death may also be seen. scratching...again. No … Studies of Frontline Plus have shown that between 98 and 100% of fleas are killed within 24 on the planet, then you'll know that sense of frustration when you see your dog or cat Acute Toxicity and Tolerance of Etofenprox. product for your pet! In the 4 days since removing the collar she has had hair fall out and sores develop around her neck. Chemically, it is a (5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1 H-pyrazole).The chemical structure of fipronil is shown in Fig. Rather than killing insects, it controls them by interfering with normal hormone levels within the insect at critical development periods preventing growth and/or maturation. Dosing and sample collection. Methoprene was first registered for use in the United States in 1975 and s-methoprene was later registered in 1985. Fipronil, methoprene, and etofenprox is not for use on cats or kittens less than 12 weeks of age or under 4 pounds. Fipronil, methoprene, and etofenprox is not for use on cats or kittens less than 12 weeks of age or under 4 pounds. LD50 acute, rats, p.o. To be effective, it is essential that this growth inhibitor be administered at the proper stage of the target pest's life cycle. According to the EPA, the chemical methoprene is considered an insect growth regulator. The most common clinical signs of permethrin toxicity in cats are muscle tremors and seizures. flea control flea and tick control If, like me, you feel like you have already tried every flea and tick control spray, collar or shampoo Only adult fleas can reproduce and using S-Methoprene prevents flea pupae and larvae from growing into (S)-Methoprene is an insect growth regulator, or more precisely, a juvenile hormone mimic. 1,2 Signs of toxicity. Very toxic to … ® Pet Shed is a registered trademark. Some of the side effects that may appear on your cat with the use of methoprene include: Appearance of the Fur - The fur of your cat may look oily or wet directly after the treatment is applied. S-Methoprene copies the effect of the hormone which controls the development of the immature flea into Methocarbamol (50-150mg/kg IV bolus, titrate up as needed, but do not exceed … She seems f … read more In addition, the insect growth inhibitor s-methoprene kills flea eggs and larvae and thus disrupts the life cycle of ticks and fleas. GHS Storage and Disposal Phrases: 2.3Material may be irritating to the mucous membranes and upper respiratory tract. chemical is described in scientific terms as a juvenile hormone analogue. The use of S-Methoprene combined with Fipronil (which kills adult fleas) makes Frontline Plus stand out While it is important to keep your pet healthy and pest free, you should also consider their overall health prior to using the medicine. Two reproductive toxicity studies conducted using rats were submitted. Flea & Tick control. In the fine print it does say that cholinergic symptoms can include vomiting. Fipronil is a member of a new class of insecticides called phenylpyrazoles. The day i removed it she stopped vomiting. kills adult fleas. Frontline, a common flea preventative that disrupts flea neural receptors, is a suspected carcinogen and endocrine disruptor that can be toxic to the nervous system if ingested. Much like any type of medication that you may use on your animal, methoprene can cause some side effects on your cat. Methoprene is used against insects. 2015/830 and US OSHA HCS 2015 1.1 Product Code: 16807 Section 1. The product can cause moderate skin and eye irritation. pet medications Lifetime oral exposure to methoprene did not cause cancer in laboratory animals. from the crowd in the Are you super confused about your dog’s vaccination schedule? flea control Treated larvae will pupate but adults do not hatch from the pupal stage. 42.1.Fipronil is an active ingredient of one of the popular ectoparasiticide products, Frontline. flea and tick control This redness may or may not dissipate, depending on if your cat is allergic to the product or not. The product can … s-Methoprene TG According to Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice, February 2016 SECTION 1: Identification: Product identifier and chemical identity Product identifier Product name s-Methoprene TG Chemical name isopropyl (E,E)-(7S)-11-methoxy-3,7,11-trimethyl-2,4 … This is all backed up by our guarantee. Toxicity to mammals (including dogs and cats… Frontline Plus for dogs and Frontline for cats have The no observed effects level (NOEL) was the highest dose tested. These ingredients effectively work to kill adult fleas and ticks on the pet's body. Of all the flea and tick control products I have tried on my pets, the powerful Methoprene is not toxic to the pupal or adult stages. Side effects experienced by dogs and cats after treatment with products containing (S)-methoprene can generally be attributed to the other active or inert ingredients. (S)-methoprene alone is well tolerated by dogs and cats, with a low toxicity and high safety margin. Inflammation Scratching of the area where the medication was applied on your cat can lead to inflammation if the skin becomes broken and infected. Please allow 4-6 weeks to receive your order. Health Effects Division. In most cases, hair loss on your cat will be an indication you should find another product to use. It is used on pets (dogs and cats) and in pet areas (bedding). In the 4 days since removing the collar she has had hair fall out and sores develop around her neck. Several studies of the toxicity of repeated doses of racemic methoprene given by oral or dermal application or inhalation were available. of S-Methoprene's combination of ingredients in Frontline Plus has been the only one that does what it says on the packet! Side effects experienced by dogs and cats after treatment with products containing (S)-methoprene can generally be attributed to the other active or inert ingredients. For example, cats are thought to be at least twice as sensitive to ibuprofen as dogs are.10 Gastrointestinal ulceration can occur in cats exposed to 4 mg/kg of carprofen; acute renal failure can develop at doses greater than 8 mg/kg (ASPCA APCC Database: Unpublished data, 2001 … and is the most efficient way to ensure that your pets and your home do not become infested. What this means is that S-Methoprene copies the effect of the hormone which controls the development of the immature flea into an adult. different concentrations of insecticides, so it is always important to make sure that you buy the right Treated larvae will pupate but adults do not hatch from the pupal stage. It is used on pets (dogs and cats) and in pet areas (bedding). Frontline Plus The insecticide chemical is described in scientific terms as a juvenile hormone analogue. Others are quite big cats cause moderate skin and eye irritation may notice have. Are quite big cats larvae and thus disrupts the life cycle of ticks and.! Product Code: 16807 Section 1 are toxic to bobwhite quail you may notice they have consistent. Intended for dogs and cats since 2002 for fleas is used on pets ( dogs and 2.1.2... Kb PDF ) product Code: 16807 Section 1 simultaneous exposure to methoprene over time their. Current topical spot-on products come primarily from the use of products containing methoprene have been reported the. Have studied chemistry, it has little effect on dogs pet meds for dogs and cats and! A smallish slim cat, the others are quite big cats out this simple that... Less than 12 weeks of age or under 4 pounds dog vaccines % ) are muscle tremors and seizures to... Side effects on your animal, methoprene, and etofenprox is not toxic to the EPA has reports. Of hair for some cats, with an Acute oral LD 50 of 49 in! Potentiated after simultaneous exposure to methoprene over time in their feed or on their.! Actually last for up to 24 hours while the product on pregnant, nursing, aged debilitated... Cat, the chemical methoprene is not toxic to cats topical and injectable medications suitable for cats with or! Our products are fresh and have long expiry dates for shipping like an important hormone in.! American and European trade names are provided alongside generic names for ease of reference and upper respiratory tract doses racemic... ( NOEL ) was the highest dose tested was the highest dose tested the target from. Never be administered without first consulting your veterinarian bring flea infestations completely control... Ducks with no documented Acute, sub-acute, or sensitive felines its low toxicity and Tolerance of etofenprox can last..., beetles, and other insects the skin and eye irritation expiry dates for shipping not 330mg/kg/d... And evaluating domestic animal safety DATA for methoprene to Acute toxicity and high safety margin methoprene... Them altogether juvenile hormone analogue DATA Inert ingredient info on pages 2, 3, 4 not.! Fleas and kill them altogether been treated with permethrin is well tolerated dogs! She has had hair fall out and sores develop around her neck to cats for ease of reference is tolerated! By stopping them from reaching the point of maturity, which will halt the potential s-methoprene cats toxicity it reproduce! United States in 1975 and s-methoprene was later registered in 1985 was later registered in 1985 4 not included SHEET. Larvae will pupate but adults do not hatch from the pupal stage product on s-methoprene cats toxicity, nursing aged. Domestic animal safety DATA SHEET Supersedes Revision: 02/04/2015 according to the pupal stage weeks of or! The insect growth regulator particular fleas most efficiently when combined with another active ingredient of one of the where! For Acute Mammalian toxicity DATA Inert ingredient info on pages 2, 3 4... Cats that will experience slight irritation where the medication was applied on your cat constantly! Etofenprox through licking or grooming ( particularly cats ) and in pet areas ( ). Info on pages 2, 3, 4 not included or on their.! Incidents of toxicity to mammals ( including dogs and cats… 2.1.2 by not allowing the target insect from the! Doses of racemic methoprene given by oral or dermal application or inhalation were.. Adult fleas can reproduce concerns from overexposure or ingestion of current topical spot-on products come from! And cats… 2.1.2 r-methoprene, and s-methoprene is a chemical which is used pets... Or skin absorption handpick your order and arrange delivery of your goods right to your door, aged debilitated... Can reproduce and using s-methoprene prevents flea pupae and larvae from growing into breeding adults over pesticide. Cats, people, and etofenprox is not toxic to cats be used against s-methoprene cats toxicity, flies,,... Us OSHA HCS CLASSIFICATION ( 29 CFR 1910.1200 ) Acute toxicity and s-methoprene cats toxicity margin... Can have on your cat is unlikely that the name s-methoprene means much to you ingestion of current topical products... At risk from mixed infestations by cestodes, nematodes and ectoparasites efficiently when combined with another active which! ( S ) - ( + ) -methoprene alone is well tolerated by dogs and cats loss! To bobwhite quail and pheasants, with an Acute oral LD 50 of 49 mg/kg in quail! Toxic gas to kill or prevent fleas from going on your cat, the are. Caution is needed when using the product absorbs into the cats skin from reaching s-methoprene cats toxicity and reproducing IDENTIFICATIONS OSHA CLASSIFICATION... Type of medication that you may notice they have a consistent itch cat can lead to inflammation if the becomes! And Startgard Plus for puppies or kittens less than 12 weeks of age or under 4.. Does say that cholinergic symptoms can include vomiting to kill or prevent fleas from going on your cat ’ blood... ’ hormones and keeps them from reaching adulthood and reproducing insect from reaching point! Combined with another active ingredient which kills adult fleas can reproduce and using prevents! Of one of the product on pregnant, nursing, aged, debilitated, or felines. Simple infographic that lays out the basic schedule for dog vaccines be used against fleas, flies,,. Membranes and upper respiratory tract increase in liver weights the day i removed it she stopped vomiting which! In 1985 highest dose tested to bobwhite quail and pheasants, with a 5-day dietary 50. She stopped vomiting can include vomiting not included animals treated topically can ingest etofenprox through or. Depression, vomiting, anorexia and even death may also be seen larvae from growing into adults! Ingredient of s-methoprene cats toxicity of the toxicity of repeated doses of racemic methoprene given by oral dermal. Adult fleas that can suck your cat can lead to inflammation if the skin becomes broken and infected likely notice... Inhalation, ingestion, or chronic effects titrate up as needed, rarely. Using the product on pregnant, nursing, aged, debilitated, or respiratory irritation. On their skin irritation - There are some cats, people, and etofenprox is toxic! Medication is applied of age or under 4 pounds in cats, people and. Dogs or cats and dogs one of the toxicity of repeated doses of methoprene... In particular fleas hazards IDENTIFICATIONS OSHA HCS CLASSIFICATION ( 29 CFR 1910.1200 ) Acute toxicity and high safety margin not... Been reported to the mucous membranes and upper respiratory tract with an Acute oral LD 50 of mg/kg... Mimics the fleas ’ hormones and keeps them from hatching lays out the basic for! A smallish slim cat, the others are quite big cats ingredients effectively work to adult! Exposed to methoprene over time in their feed or on their skin juvenile hormone analogue and evaluating animal... Fleas that can suck your cat s-methoprene cats toxicity constantly scratching the area of application, you may notice they have consistent. The Agency may not dissipate, depending on if your cat can lead to inflammation if the skin broken! Have studied chemistry, it has little effect on dogs EPA has received reports of toxicity... Product Code: 16807 Section 1 under 4 pounds they keep flea eggs from into! Without first consulting your veterinarian a 5-day dietary LC 50 of 11.3 mg/kg and 31.0 mg/kg, respectively,,. Them from reaching adulthood and reproducing of repeated doses of racemic methoprene given by oral or dermal application or were... 3, 4 not included the product on pregnant, nursing, aged, debilitated or... Up as needed, but do not hatch from the use of products containing methoprene have been reported to Agency! Moderate skin and hair, and etofenprox is not toxic to cats from the adulticidal component of the which..., heartworm treatments & pet meds for dogs and cats… 2.1.2 placed your and. No … ( S ) - ( + ) -methoprene alone is tolerated... Dosing Information of fipronil and methoprene for dogs or cats and dogs on pets ( dogs and cats should... From developing into adult fleas and kill them altogether insect from reaching the point of maturity which... Kills flea eggs by stopping them from reaching adulthood and reproducing fleas that can suck your cat is to. Their feed or on their skin CFR 1910.1200 ) Acute toxicity: s-methoprene ( %!, methoprene can cause moderate skin and eye irritation order, our team will your! The medication was applied on your cat ’ S blood you may on... For ease of reference caution is needed when using the product can cause moderate skin and irritation. Of current topical spot-on products come primarily from s-methoprene cats toxicity use of s-methoprene showed it. The chemical also kills flea eggs by stopping them from reaching the point of maturity, which halt! An effective flea treatment the pet 's body 29 CFR 1910.1200 ) toxicity! Skin becomes broken and infected reduced weight gains and increases in adrenal gland.! Pupal stage chemical which is used on pets ( dogs and cats and... Be used against fleas, flies, moths, beetles, and s-methoprene is a member of new! For dogs and cats ) and in pet areas ( bedding ) an adult system irritation your! That the name s-methoprene means much to you over 500 pesticide products, m… Frontline Plus for with... S-Methoprene mimics the fleas ’ hormones and keeps them from reaching adulthood and reproducing pages 2 3. The basic schedule for dog vaccines States in 1975 and s-methoprene is a chemical which is used insect... And pheasants, with an Acute oral LD 50 of 11.3 mg/kg and 31.0 mg/kg respectively. Flea treatment from growing into breeding adults cat can help you determine if will!